Blood components

Fresh plasma in quarantine

DEFINITION AND HOW THEY ARE OBTAINED

Units of fresh plasma from a single donor are kept frozen in quarantine until at least 2 months after donation. After this period, the donor donates again and thus undergoes a new analysis. If the second analysis produces another negative result, the plasma from the first donation is released for transfusion purposes. This method minimises the risk of using a unit of plasma that may have been obtained during an incubation period of any of the viruses under analysis.

COMPOSITION AND CHARACTERISTICS

Volume:
  • Between 570 and 600 ml, the units obtained with a Haemonetic separator.
  • Between 220 and 410 ml, the units obtained with a Cobe TRYMA separator.
Coagulation factor content:
  • Factor VIII 0.77 UI/ml (between 0.37 and 1.17)
  • Factor V 0.94 UI/ml (between 0.56 and 1.32)
  • Factor II 0.87 UI/ml (between 0.73 and 1.01)
  • Fibrinogen 3.21 g/l (between 1.67 and 4.57)

ANALYSIS RESULTS

  • ABO group and Rh factor.
  • Irregular antibodies: negative.
  • Hepatitis B surface antigen (HBsAg): negative.
  • Hepatitis C virus antibodies (Anti-HCV): negative.
  • Human immunodeficiency virus antibodies (Anti-HIV 1/2): negative.
  • Lues serology: negative
  • HCV RNA (PCR): negative.

RECIPIENT

Collapsible plastic bags.

IDENTIFICACION

By labels stating: name of centre, type of product, ABO group and Rh (D) factor, unit number, date of extraction, expiry date, results of completed analysis, type of anticoagulant, and instructions for storage and administration.

STORAGE

At -30ºC.

SHELF LIFE

3 years.

TREATMENT

The units of plasma in quarantine may be fractionated into subunits.