Recreation of the embryonic niche for the production of hematopoietic stem cells and their derivatives in human gastruloids.

Principal Investigator

Núria Nogués

File

PLEC2021-007518

Duration

2021 – 2024

Funded by

Agencia Estatal de Investigación

Funded by the Ministry of Science and Innovation/State Research Agency (Digital Object Identifier 10.13039/501100011033) and by the European Union "NextGenerationEU"/Plan for the Recovery, Transformation and Resilience of Spain

Objective

Generation of haemogenic human gastruloids from iPSCs that will harbour definitive haematopoietic stem cells and thus provide a renewable and ethically compatible source of blood products.