Bioengineering of induced pluripotent stem cells for advanced immunotherapy for fungal infections
Principal Investigator
Belen Alvarez
File
CPP2022-009594
Duration
2023 -2026
Funded by
Agencia Estatal de Investigación
Funded by MCIN/AEI /10.13039/501100011033 and by the European Union NextGenerationEU/PRTR.
Objective
To design and develop a new approach for immunotherapy of fungal infections beyond T cells. Our proposal is to generate allogeneic alternatives based on the CAR approach, using iPSC as starting material to produce innate immunity cells to combat fungi: NK cells and macrophages.