Clinical information
Diagnostic Utility:
This is the qualitative detection of IgG/IgM antibodies against Treponema pallidum (TP) and its determination is useful in:
- Detection of exposure to Treponema Pallidum causing Syphilis.
- Transfusion of blood components.
- Transplantation of progenitor cells, umbilical cord blood, solid organs.
- In egg and semen donors.
Method:
Chemiluminescence Microparticle Immunoassay (CMIA).
Reference Values
Possible results are: Reactive and Non-Reactive.
Diagnostic Algorithm:
In the case of a reactive Syphilis TP result, a confirmatory IgG antibody test can be requested by Immunoblot:
| Code | Test Name | Can it be requested separately? | Is it always done? |
|---|---|---|---|
| 0134 | Treponema pallidum, IgG. Confirmation by Immunoblot. | NO | NO (*) |
(*) Only performed upon request.
Turnaround Time:
Maximum 2 working days
Specimen information
Sample: Serum and/or plasma
Tube: Aliquots of 1-5 mL, plasma tubes with EDTA, heparin, or sodium citrate as anticoagulant and/or serum tubes with or without separator.
Minimum essential volume: 1 ml
Stability:
- At room temperature: ≤ 1 day
- Refrigerated 2-8 ºC: ≤ 7 days
- Sample frozen at or below -20ºC: 10 years
Transport instructions: Preferably at room temperature if it is whole blood tubes and refrigerated if it is serum and/or plasma aliquots.
Reason for rejection: Sample with a lot of hemolysis.
Administrative information
BST Code: 0131
Test Description: Treponema pallidum, Antibodies (IgG+IgM).
Synonyms: Syphilis TP
Section: Transfusion Safety Laboratory
BST Rate: Check the updated rates here.
Profiles:
Not applicable.
References
- Inserts kits de Sifilis TP Architect, Abbott.