Clinical information
Diagnostic Utility:
This is the qualitative detection of IgM antibodies against cytomegalovirus (CMV) and its determination is useful in:
- Identification of seronegative individuals, as well as seronegative donors of organs, blood products, semen, or eggs.
- Transfusion of blood products in newborns, pregnant women, patients with liver disease, and immunosuppressed patients.
- Transplantation of progenitor cells, umbilical cord blood, solid organs.
Method:
Chemiluminescence Microparticle Immunoassay (CMIA).
Reference Values
Possible results are: Reactive and Non-Reactive.
Diagnostic Algorithm:
In case of a reactive CMV anti-IgG and/or CMV anti-IgM result, the CMV DNA detection test can be requested upon request:
| Code | Test Name | Can it be requested separately? | Is it always done? |
|---|---|---|---|
| 0168 | Cytomegalovirus, DNA | Yes | No (*) |
* Only done upon request and requires a whole blood sample.
Response Time:
Maximum 2 working days.
Specimen information
Sample: Serum and/or plasma
Tube: Aliquots of 1-5 mL, plasma tubes with EDTA, citrate, or sodium heparin, and/or serum tubes with or without gel separator.
Minimum essential volume: 1 ml
Stability:
- At room temperature: ≤ 4 days
- Refrigerated at 2-8 ºC: ≤ 14 days
- Sample frozen at or below -30ºC: 10 years
Transport instructions: Preferably at room temperature if whole blood tubes, and refrigerated if serum and/or plasma aliquots.
Reason for rejection: Highly hemolyzed sample.
Administrative information
BST Code: 0162
Test Description: Cytomegalovirus, Antibodies IgM
Synonyms: CMV IgM
Section: Transfusional Safety Laboratory
BST Rate: Check the updated rates here.
Profiles:
Test 0162 Cytomegalovirus, Antibodies IgM Screening can be requested alone or within the following profile:
| Profile | Included Tests |
|---|---|
| CMV antibodies detection profile |
0165 Cytomegalovirus, Antibodies IgG Screening 0162 Cytomegalovirus, Antibodies IgM Screening |
References
- Inserts kits de CMV IgM Architect, Abbott.
Quality
BST holds ISO 9001, ISO 14001, and OSHAS 18001 quality certifications, as well as the European Excellence 500+ seal. BST is accredited by CAT, JACIE-FACT, FACT-NETCORD, and EFI, and complies with Good Manufacturing Practice (GMP) and Good Distribution Practice (GDP) guidelines.