Clinical information
Diagnostic Utility:
This is the confirmatory detection of IgG antibodies against human T-cell lymphotropic virus type I (HTLV-I) and type II (HTLV-II), using recombinant protein antigens and synthetic peptides. Its determination is useful for:
- Confirmation of the presence of specific IgG antibodies to HTLV.
- Blood components transfusion.
- Transplantation of progenitor cells, solid organs, and tissues.
- Infectious disease screening of egg and semen donors.
Method:
Strip immunoassay.
Reference Values
Possible results are: HTLV, HTLV I, HTLV II, Indeterminate, and Non-Reactive.
Diagnostic Algorithm:
In the event of a reactive result in the confirmatory test for HTLV-I/II antibodies by Immunoblot, PCR can be requested to detect HTLV I proviral DNA.
| Code | Test Name | Can It Be Requested Separately? | Is It Always Done? |
|---|---|---|---|
| 0178 | HTLV I, Proviral DNA | YES | NO (*) |
(*) Upon request
Turnaround Time:
Maximum of 15 working days.
Specimen information
Sample: Serum and/or plasma
Tube: 1-5 mL aliquots, plasma tubes with EDTA, citrate or heparin as anticoagulant and/or serum tubes with and without gel separator.
Minimum essential volume: 1 ml
Stability:
- At room temperature: ≤ 4 days
- In refrigeration 2 - 8 ºC: ≤ 7 days
- Sample frozen equal to or below -20ºC: 10 years
Transport instructions: Preferably at room temperature and/or refrigerated if they are whole blood tubes and frozen if they are serum and/or plasma aliquots.
Reason for rejection: Sample very hemolyzed, plasma tubes with heparin as anticoagulant.
Administrative information
BST Code: 0174
Test Description: HTLV I/II, Antibodies (IgG). Confirmation by Immunoblot
Synonyms: anti-HTLV I/II
Section: Transfusion Safety Laboratory
BST Rate: Check the updated rates here.
Profiles:
N/A.
References
- Inserts kits test FUJIREBIO INNO-LIA HTLV I/II Score