Clinical information
Diagnostic Utility:
This involves the detection of specific DNA from human T-cell lymphotropic virus type I/II (HTLV-I/II), and its determination is useful in:
- Detection of proviral DNA from HTLV-I/II virus.
- Transfusion of blood components.
- Transplantation of progenitor cells, solid organs, and tissues.
- Screening for infectious diseases in egg and semen donors.
Method:
Polymerase Chain Reaction (PCR).
Reference Values
Possible results are: Reactive and Nonreactive
Diagnostic Algorithm:
Not applicable.
Response Time:
Maximum 30 natural days.
Specimen information
Sample: Whole blood and/or leukocyte layer.
Tube: Plasma tubes with EDTA or citrate as anticoagulant.
Minimum essential volume: 2 ml
Stability:
- At room temperature: ≤ 3 days
- In refrigeration 2-8 ºC: ≤ 7 days
Transport instructions: Preferably send the whole blood tubes refrigerated.
Rejection reason: Insufficient sample volume.
Administrative information
BST Code: 0178
Test Description: HTLV I/II, proviral DNA
Synonyms: HTLV I/II DNA, HTLV I/II PCR
Section: Transfusion Safety Laboratory
BST Rate: Check the updated rates here.
Profiles:
Not applicable.
References
- Piron M, Salvador F, Caballero E, Sánchez-Montalvá A, Bes M, Casamitjana N, Puig L, Molina I, Sauleda S. HTLV-1/2 Infection in Blood Donors from a Non-Endemic Area (Catalonia, Spain) between 2008 and 2017: A 10-Year Experience. Viruses. 2022 Sep 6;14(9):1975.