Clinical information
Diagnostic Utility:
This is the qualitative detection of IgG+IgM antibodies against the core antigen of the hepatitis B virus (HBV) and its determination is useful in:
- Identification of exposure to the hepatitis B virus.
- Blood product transfusion, transplantation of progenitor cells, umbilical cord blood cells, solid organs, and tissues.
Method:
Chemiluminescence Microparticle Immunoassay (CMIA).
Reference Values
Possible results are: Reactive and Non-reactive.
Diagnostic Algorithm:
If the result of anti-HBc (IgG+IgM) is reactive, the anti-core antibodies (IgM) detection test and the anti-HBs antibodies detection test are performed.
| Code | Name of the test | Can it be requested separately? | Is it always done? |
|---|---|---|---|
|
0160 0100 |
Hepatitis B, Anti-core Antibodies (IgM). Screening Hepatitis B, Anti-surface Antigen Antibodies. |
Yes Yes |
Yes Yes |
Response Time:
Maximum 2 working days
Specimen information
Show: Serum and/or plasma
Tube: Aliquots of 1-5 mL, plasma tubes with EDTA, sodium heparin, sodium citrate, potassium oxalate, CPD, CPDA-1, or ACD as anticoagulants and/or serum tubes with or without gel separator.
Minimum essential volume: 1 ml
Stability:
- At room temperature: ≤ 3 days
- In refrigeration: ≤ 14 days
- Frozen sample equal to or below -30°C: 10 years
Transport instructions: Preferably at room temperature if they are total blood tubes and refrigerated if they are serum and/or plasma aliquots.
Reason for rejection: Sample very hemolyzed.
Administrative information
BST Code: 0106
Test Description: Hepatitis B, Anti-core antibodies (IgG+IgM). Screening.
Synonyms: Anti-HBc
Section: Transfusion Safety Laboratory
BST Fee: Check the updated fees here.
Profiles:
N/A.