Clinical information
Diagnostic Utility:
This is the detection of IgG antibodies against Human T-cell Lymphotropic Virus Type I (HTLV-I) and Type II (HTLV-II), and its determination is useful for:
- Detecting HTLV I/II virus infection.
- Blood component transfusion.
- Transplantation of progenitor cells, solid organs, and tissues.
- Screening infectious diseases in egg and semen donors.
Method:
Chemiluminescence Microparticle Immunoassay (CMIA).
Reference Values
Possible results are: Reactive and Non-Reactive.
Diagnostic Algorithm:
In case of a reactive result for HTLV I/II anti-IgG, a confirmatory test for HTLV-I/II antibodies by Immunoblot and PCR for HTLV I/II proviral DNA may be requested:
| Code | Test Name | Can it be requested separately? | Is it permanent? |
|---|---|---|---|
|
0174 0178 |
HTLV I/II, Antibodies (IgG). Confirmation by Immunoblot. HTLV I, proviral DNA |
YES YES |
NO (*) NO (**) |
* Only performed upon request.
** Performed upon request and requires whole blood.
Turnaround Time:
Maximum 2 working days.
Specimen information
Sample: Serum and/or plasma
Tube: 1-5 mL aliquots, plasma tubes with EDTA, potassium oxalate, sodium citrate, ACD, CP2D, CPD, or CPDA-1 as anticoagulant and/or serum tubes with and without gel separator.
Minimum essential volume: 1 ml
Stability:
- At 15-30 ºC: ≤ 3 days
- In refrigeration at 2-8 ºC: ≤ 14 days
- Frozen sample equal to or below -20ºC: 10 years
Transport instructions: Preferably at room temperature and/or refrigerated if they are whole blood tubes, and frozen if they are serum and/or plasma aliquots.
Reason for rejection: Highly hemolyzed samples.
Administrative information
BST Code: 0171
Test Description: HTLV I/II, IgG Antibodies. Screening
Synonyms: anti-HTLV I/II
Section: Transfusion Safety Laboratory
BST Rate: Check the updated rates here.
Profiles:
N/A.
References
- Inserts kits test ABBOTT ARCHITECT HTLV-I/II